1. SylabUZ
2. Wydział Nauk Biologicznych
3. semestr zimowy 2022/2023
4. WNB - oferta ERASMUS - Program Erasmus
5. Applications of bioinformatics

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Applications of bioinformatics - opis przedmiotu

Cel przedmiotu

Learning about bioinformatics research methods, bioinformatics databases/services and biological literature databases.
Getting to know selected bioinformatics programs and their applications. 

Wymagania wstępne

Zapisz zmiany

Computer and Internet skills. 

Zakres tematyczny

Lecture

Bioinformatics databases/services. Analysis of the evolution of organisms and organisms' attractors. Evolutionary distances. Phylogenetic trees and algorithms of their creation. Multiple alignment of sequences. 2D and nD dot-matrix. Dot-matrix cleaning methods. Estimating the significance of the similarity of the compared sequences. The Pan factor and its application. Genetic semihomology. Detection of insertions, deletions and types of semihomology. Determining representatives. Modeling and analysis of protein structures. Analysis of cancer development. Methods of bioinformatics functionality and their implementation.

 

Laboratory

The subject of practical laboratory exercises relating to and consolidating the knowledge from the lectures:
- analysis of the evolution of organisms, including organisms of industrial importance,
- modeling and analysis of protein structures,
- applications of dot-matrix,
- phylogenetic trees,
- implementation of methods of bioinformatics functionality. 

Metody kształcenia

Lecture with multimedia presentations (PowerPoint) and the use of bioinformatics databases/services and specialized bioinformatics programs. Practical exercises with the use of biological databases and specialized bioinformatics programs. 

Efekty uczenia się i metody weryfikacji osiągania efektów uczenia się

Opis efektu	Symbole efektów	Metody weryfikacji	Forma zajęć

Warunki zaliczenia

Lecture - the pass mark is to obtain a positive grade from written bioinformatics essay.

Laboratory - the condition for obtaining credit are positive grades from all laboratory exercises planned for implementation under the laboratory program. 

Literatura podstawowa

1. Baxevanis A.D, Ouellette B.F.F. Bioinformatics, John Wiley & Sons, Inc. 2001.
2. Berg J.M, Stryer L., Tymoczko J., Gatto G., Biochemistry, WH Freeman, 2019.
3. Higgs P.G., Attwood T.K., Bioinformatics and Molecular Evolution,  Blackwell Publishing Ltd. 2005.
4. Xiong J., Essential Bioinformatics, Cambridge University Press, 2012.

Literatura uzupełniająca

Uwagi

Zmodyfikowane przez dr hab. inż. Andrzej Kasperski, prof. UZ (ostatnia modyfikacja: 04-05-2022 17:13)