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Molecular organization of the cell - course description

General information
Course name Molecular organization of the cell
Course ID 13.9-WB-P-MOC-S20
Faculty Faculty of Exact and Natural Sciences
Field of study WNB - oferta ERASMUS
Education profile -
Level of studies Erasmus programme
Beginning semester winter term 2021/2022
Course information
Semester 2
ECTS credits to win 5
Course type obligatory
Teaching language english
Author of syllabus
  • dr Elżbieta Heger
  • prof. dr hab. Aleksander Sikorski
Classes forms
The class form Hours per semester (full-time) Hours per week (full-time) Hours per semester (part-time) Hours per week (part-time) Form of assignment
Laboratory 30 2 - - Credit with grade
Lecture 25 1,67 - - Exam

Aim of the course

The primary objective is to provide a dynamic cellular processes and cell signaling and signal transduction pathways of integration.

Prerequisites

Biology, biochemistry, biophysics, genetics.

Scope

Lecture
Signaling at the intercellular level and inside the cell. Examples of receptor structure and function. Discussion of the basic signal transduction pathways. Integration of individual signal pathways, role of scaffold proteins (scaffold). The role of membrane rafts in signaling.

Lab
Analysis of quantitative and qualitative composition of membrane signaling domains. Construction and organization of key domains of anchor proteins (molecular scaffold proteins). Detection, structure and function of glycosylated proteins. Examples of signal transduction pathway disorders. Modern pharmacotherapy strategies regulating signal reception.

Teaching methods

LECTURE - the method of delivery: information lecture with the use of multimedia presentations, examples of problem solving LABORATORY - the method of delivery: talk about the analytical methods used, the analysis of experimental results, the method practical: the tasks of laboratory analytical work using selected methods of analysis of structure and function of living cells .

Learning outcomes and methods of theirs verification

Outcome description Outcome symbols Methods of verification The class form

Assignment conditions

The condition for passing is to obtain a positive result from laboratory classes and a positive result from the exam. Laboratory exercises: the condition for passing is to obtain positive marks from all laboratory exercises planned for implementation as part of the laboratory program, ie: 3 tests (3 questions - positive assessment over 50% of points obtained), independently prepared laboratory reports. The final rating is the arithmetic mean of partial grades. Lecture: An exam lasting 60 minutes contains 3 open questions. To qualify for a satisfactory grade, it is necessary to obtain a minimum of 50% of points.

Recommended reading

1. Harvey Lodish i in., Molecular Cell Biology, 6th Edition, Freeman 2008.

2. Bruce Alberts i in., Molecular Biology of the Cell, 5th Edition, Garland Sci. 2007.

3. Gerald Karp, Cell and Molecular Biology: Concepts and Experiments, Study Guide, 5th Edition, Wiley 2007. 

Further reading

1. Bruce Alberts i in., Podstawy Biologii Komórki, PWN 2009 (copyright 2005).

2. Wincenty M. Kilarski, Strukturalne Podstawy Biologii Komórki, PWN 2012 (copyright 2005).

3.  red. Zofia Bielańska- Osuchowska Słownik Biologii Komórki, wyd II, PAU 2008.

Notes


Modified by dr Ewa Skorupka (last modification: 15-04-2021 12:43)