1. SylabUZ
2. Wydział Nauk Ścisłych i Przyrodniczych
3. semestr zimowy 2021/2022
4. WNB - oferta ERASMUS - Program Erasmus
5. Molecular organization of the cell

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Molecular organization of the cell - opis przedmiotu

Cel przedmiotu

The primary objective is to provide a dynamic cellular processes and cell signaling and signal transduction pathways of integration.

Wymagania wstępne

Zapisz zmiany

Biology, biochemistry, biophysics, genetics.

Zakres tematyczny

Lecture
Signaling at the intercellular level and inside the cell. Examples of receptor structure and function. Discussion of the basic signal transduction pathways. Integration of individual signal pathways, role of scaffold proteins (scaffold). The role of membrane rafts in signaling.

Lab
Analysis of quantitative and qualitative composition of membrane signaling domains. Construction and organization of key domains of anchor proteins (molecular scaffold proteins). Detection, structure and function of glycosylated proteins. Examples of signal transduction pathway disorders. Modern pharmacotherapy strategies regulating signal reception.

Metody kształcenia

LECTURE - the method of delivery: information lecture with the use of multimedia presentations, examples of problem solving LABORATORY - the method of delivery: talk about the analytical methods used, the analysis of experimental results, the method practical: the tasks of laboratory analytical work using selected methods of analysis of structure and function of living cells .

Efekty uczenia się i metody weryfikacji osiągania efektów uczenia się

Opis efektu	Symbole efektów	Metody weryfikacji	Forma zajęć

Warunki zaliczenia

The condition for passing is to obtain a positive result from laboratory classes and a positive result from the exam. Laboratory exercises: the condition for passing is to obtain positive marks from all laboratory exercises planned for implementation as part of the laboratory program, ie: 3 tests (3 questions - positive assessment over 50% of points obtained), independently prepared laboratory reports. The final rating is the arithmetic mean of partial grades. Lecture: An exam lasting 60 minutes contains 3 open questions. To qualify for a satisfactory grade, it is necessary to obtain a minimum of 50% of points.

Literatura podstawowa

1. Harvey Lodish i in., Molecular Cell Biology, 6th Edition, Freeman 2008.

2. Bruce Alberts i in., Molecular Biology of the Cell, 5th Edition, Garland Sci. 2007.

3. Gerald Karp, Cell and Molecular Biology: Concepts and Experiments, Study Guide, 5th Edition, Wiley 2007. 

Literatura uzupełniająca

1. Bruce Alberts i in., Podstawy Biologii Komórki, PWN 2009 (copyright 2005).

2. Wincenty M. Kilarski, Strukturalne Podstawy Biologii Komórki, PWN 2012 (copyright 2005).

3.  red. Zofia Bielańska- Osuchowska Słownik Biologii Komórki, wyd II, PAU 2008.

Uwagi

Zmodyfikowane przez dr Ewa Skorupka (ostatnia modyfikacja: 15-04-2021 12:43)