1. SylabUZ
2. Wydział Lekarski i Nauk o Zdrowiu
3. semestr zimowy 2023/2024
4. WLiNZ - oferta ERASMUS / Lekarski - jednolite magisterskie sześcioletnie
5. Elective subject- Mechanisms of antibiotics action and bacterial drug resistance strategies

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Elective subject- Mechanisms of antibiotics action and bacterial drug resistance strategies - opis przedmiotu

Cel przedmiotu

The course aims to learn how antibiotics work on bacterial cells and present the complex mechanisms responsible for resistance to these substances and the genes that determine the emergence of resistance —acquainted with the problem of growing antibiotic resistance of pathogenic and commensal bacteria the consequences for human health.

 

Wymagania wstępne

Zapisz zmiany

 Completed Microbiology course

Zakres tematyczny

Overview of the most common drug resistance mechanisms by the antibiotic target.

1. Antibacterial substances causing the loss of cell wall integrity: β-lactams, glycopeptides, and phosphonic acid derivatives and resistance mechanisms.

2. Antibacterial substances influencing bacterial cell membranes: polymyxins, lipopeptides, and resistance mechanisms.

3. Antibacterial substances inhibiting the synthesis of nucleic acids: quinolones, ansamycins, and resistance mechanisms.

4. Antibacterial substances inhibiting protein synthesis: macrolides, ketolides, aminoglycosides, glycylcyclines, oxazolidinones, and resistance mechanisms.

5. Multi-drug resistance - how to approach it

6. Alert pathogens - management

Metody kształcenia

Provide content with multimedia presentations and discussion in English - classes adapted to direct implementation and using e-learning platforms.

Efekty uczenia się i metody weryfikacji osiągania efektów uczenia się

Opis efektu	Symbole efektów	Metody weryfikacji	Forma zajęć

Warunki zaliczenia

The condition for passing the course is obtaining a positive grade on the test summarizing the discussed issues. The test includes ten open and/or closed questions; 60% of correct answers are required to pass the course successfully. One excused absence is allowed, which must be made up in writing or orally, within the time limit agreed with the teacher. 

Literatura podstawowa

 1. Gualerzi C.O., Brandi L., Fabbretti A., Pon C.L. Antibiotics: Targets, Mechanisms and Resistance, ISBN: 978-3-527-33305-9, December 2013

Literatura uzupełniająca

Uwagi

Zmodyfikowane przez dr hab. Katarzyna Baldy-Chudzik, prof. UZ (ostatnia modyfikacja: 11-05-2023 14:39)