SylabUZ
| Course name | Elective subject- Mechanisms of antibiotics action and bacterial drug resistance strategies |
| Course ID | 12.9-WL-LekAM-ES-MeAnBlReE- 22 |
| Faculty | Faculty of Medicine and Health Sciences |
| Field of study | WLiNZ - oferta ERASMUS / Medical |
| Education profile | - |
| Level of studies | Long-cycle studies leading to MS degree (6 years) |
| Beginning semester | winter term 2023/2024 |
| Semester | 5 |
| ECTS credits to win | 1 |
| Course type | obligatory |
| Teaching language | polish |
| Author of syllabus |
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| The class form | Hours per semester (full-time) | Hours per week (full-time) | Hours per semester (part-time) | Hours per week (part-time) | Form of assignment |
| Class | 15 | 1 | - | - | Credit |
The course aims to learn how antibiotics work on bacterial cells and present the complex mechanisms responsible for resistance to these substances and the genes that determine the emergence of resistance —acquainted with the problem of growing antibiotic resistance of pathogenic and commensal bacteria the consequences for human health.
Completed Microbiology course
Overview of the most common drug resistance mechanisms by the antibiotic target.
1. Antibacterial substances causing the loss of cell wall integrity: β-lactams, glycopeptides, and phosphonic acid derivatives and resistance mechanisms.
2. Antibacterial substances influencing bacterial cell membranes: polymyxins, lipopeptides, and resistance mechanisms.
3. Antibacterial substances inhibiting the synthesis of nucleic acids: quinolones, ansamycins, and resistance mechanisms.
4. Antibacterial substances inhibiting protein synthesis: macrolides, ketolides, aminoglycosides, glycylcyclines, oxazolidinones, and resistance mechanisms.
5. Multi-drug resistance - how to approach it
6. Alert pathogens - management
Provide content with multimedia presentations and discussion in English - classes adapted to direct implementation and using e-learning platforms.
| Outcome description | Outcome symbols | Methods of verification | The class form |
The condition for passing the course is obtaining a positive grade on the test summarizing the discussed issues. The test includes ten open and/or closed questions; 60% of correct answers are required to pass the course successfully. One excused absence is allowed, which must be made up in writing or orally, within the time limit agreed with the teacher.
1. Gualerzi C.O., Brandi L., Fabbretti A., Pon C.L. Antibiotics: Targets, Mechanisms and Resistance, ISBN: 978-3-527-33305-9, December 2013
Modified by dr hab. Katarzyna Baldy-Chudzik, prof. UZ (last modification: 11-05-2023 14:39)
