1. SylabUZ
2. Wydział Lekarski i Nauk o Zdrowiu
3. semestr zimowy 2023/2024
4. WLiNZ - oferta ERASMUS / Lekarski - jednolite magisterskie sześcioletnie
5. Patology

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Patology - opis przedmiotu

Cel przedmiotu

The aim of education is to acquire knowledge about the mechanisms of disease development at the cellular and organ level as well as the ability to apply and interpret appropriate morphological tests. The ability to use the results of morphological and autopsy studies in connection with the symptoms of diseases for use in everyday professional practice.

Wymagania wstępne

Zapisz zmiany

Knowledge of anatomy, physiology, biochemistry, molecular biology, pathophysiology.

Zakres tematyczny

1. Digestive system pathology, part 1

Lecture: Pathology of the oral cavity

Seminar: Tumors of the salivary glands

Histological slides:

1. Fine-needle aspiration biopsy (FNAB) of pleomorphic adenoma (mixed tumor of salivary gland)

2. FNAB - Warthin tumor ("adenolymphoma", "papillary cystadenoma lymphomatosum"

3. Mixed tumor of the salivary gland

4. Warthin tumor

5. Oral cavity fibroma

6. Epulis, (peripheral) giant cell granuloma (giant cell epulis)

7. adenoid cystic carcinoma of the salivary gland

 

1. Digestive tract pathology, part 2

Lecture: Tumors of the stomach

Seminar: Inflammation and gastric ulcer disease

Histological slides:

1. Squamous cell papilloma of the esophagus

2. Squamous cell carcinoma of the esophagus

3. Fundic gland polyp (Elster polyp)

4. Diffuse advanced gastric cancer according to Lauren with lymph node metastasis

5. Intestinal cancer of the stomach according to Lauren

6. Lymphoma of the stomach (DLBCL)

7. Chronic gastritis with intestinal metaplasia

8. Ectopic gastric mucosa in the duodenum

9. Peptic ulcer of the stomach

 

1. Gastrointestinal pathology, part 3

Lecture: Tumors of the liver and pancreas

Seminar: Hepatitis and pancreatitis

Histological slides:

1. Gallbladder cancer

2. Cancer metastasis to the liver – FNAB

3. Adenocarcinoma of the colon

4. Metastasis of adenocarcinoma to the liver and lungs

5. Hepatocellular carcinoma (HCC)

6. Metastasis of hepatocellular carcinoma to the lungs

7. Neuroendocrine tumor of the appendix

8. IHC staining. Synaptophysin

9. IHC Chromogranin staining

10. IHC Ki-67 staining GIST

11. IHC CD117 staining

12. IHC CD34 staining

13. IHC Desmin staining

 

1. Pathology of the thyroid gland and adrenal glands

Lecture: Tumors of the thyroid gland and adrenal glands

Seminar: Thyroiditis

Histological slides:

1. Papillary thyroid carcinoma

2. Follicular thyroid carcinoma

3. Medullary thyroid carcinoma

4. Anaplastic thyroid carcinoma

5. Fine needle aspiration biopsy (FNAB) - benign lesion of the thyroid gland

6. FNAB- follicular thyroid carcinoma

7. FNAB- papillary thyroid carcinoma

8. FNAB- medullary thyroid carcinoma

9. FNAB- anaplastic thyroid carcinoma

 

5. Autopsy

Lecture: Tumors of the large intestine

Seminar: Colitis

 

6. Lymphatic system pathology

Lecture: Classification of leukemias and lymphomas

Seminar: Hodkin's disease

Histological slides:

1. Hodkin's disease

2. DLBCL lymphoma

3. MALT lymphoma

4. Follicular lymphoma

5. SLL lymphoma

 

7. Pathology of the nervous system

Lecture: Tumors of the central nervous system

Seminar: Alzheimer's disease

Histological slides:

1. Meningioma

2. Metastasis of breast cancer to the central nervous system

3. Glioblastoma multiforme

4. Oligodendroglioma

5. Gliomas, fibrillary astrocytoma

6. Pituitary adenoma

7. Neurocytoma

 

            8. Pathology of the male reproductive system, part 1

Lecture: Tumors of the testicle and penis

Seminar: Testicular and epididymitis

Histological preparations:

1. Seminoma

2. Embryonal carcinoma

3. Yolk sac tumor

4. Teratoma maturum

5. Choriocarcinoma

6. Hydrocele

           

            9. Pathology of the male reproductive system, part 2

Lecture: Prostate cancer and benign prostate hyperplasia

Seminar: Bladder cancer

Histological slides:

1. Benign prostatic hyperplasia

2. Prostate cancer - core needle biopsy

3. IHC beta keratin staining in prostate cancer

4. IHC AMACR staining in prostate cancer

5. Inflammation of the bladder lining (Cystitis glandularis)

6. Inflammation of the bladder lining (Cystitis cystica)

7. Urothelial carcinoma in situ

 

            10. Pathology of the urinary system Lecture: Tumors, interstitial nephritis, cysts Seminar: Transplantation

Histological slides:

1. Clear cell renal cell carcinoma

2. Chromophobe renal cell carcinoma

3. Papillary renal cell carcinoma

4. Collecting duct carcinoma

5. Angiomyololipoma renis

6. Chronic pyelonephritis

7. Oncocytoma renis/ Oncocytoma of the kidney

 

11. Pathology of the female reproductive system, part 1

Lecture: Breast cancer

Seminar: Benign breast hyperplasia

Histological slides:

1. Fibrous and cystic changes

2. Fibroadenoma

3. Ductal carcinoma in situ

4. Carcinoma ductale infiltrans

5. Carcinoma lobulare in situ

6. Infiltrating lobular carcinoma

 

            12. Pathology of the female reproductive system, part 2

Lecture: Cervical cancer, carcinoma of the uterine corpus, salpingitis, ectopic pregnancy

Seminar: Ovarian tumors

Histological slides:

1.  
2. Endometrial hyperplasia of the uterine corpus, complex hyperplasia
3. Endometrial polyp
4.  
5. Leiomyoma
6. Leiomyosarcoma
7. Granulosa cell tumor
8.  
9. Serous cystadenoma of the ovary
10. Serous adenocarcinoma of the ovary
11.  

 

13. Skin and skeletal pathology

Lecture: Malignant melanoma. Bone tumors

Seminar: Skin epithelial neoplasms

Histological slides:

1. Malignant melanoma

2. Compound melanocytic nevus

3. Seborrheic keratosis

4. Squamous cell carcinoma

5. Basal cell carcinoma

6. Epidermal cyst

7. Tricholemmal cyst

8. Neuroendocrine tumor

9. Osteosarcoma

10. Osteochondroma (exostosis, osteocartilaginous exostosis)

14. Childhood pathology

Lecture: Childhood cancers

Seminar: Hemolytic disease.

Cystic fibrosis.

Metody kształcenia

Education in the form of a laboratory, learning to recognize morphological images in a room equipped with microscopes and computers, under the supervision of an assistant. During the laboratory, participation in a series of autopsy classes in the auditorium located in the autopsy room is planned. Participation of students in the post-mortem examination. Seminars and lectures in the form of multimedia presentations.

Efekty uczenia się i metody weryfikacji osiągania efektów uczenia się

Opis efektu	Symbole efektów	Metody weryfikacji	Forma zajęć

Warunki zaliczenia

Assignment conditions

1. There are four possible absences, justified by an appropriate document certifying an illness (sick leave) or a random accident, which the student should make up for in consultation with the teacher, before the final test in a given topic section. The justification should be presented to the teacher within 3 working days of the event. Unexcused absences mean the inability to complete the course.
2. Each class is preceded by a written (entry) test. In the case of failing the test, the Student receives -2 points (minus two points) for the final test for a given topic section. It is not possible to correct written tests.
3. During the course, the student takes 4 final tests - two in the winter semester and two in the summer semester. Passing all tests is a condition for taking the final exam.

The final test consists of 40 multiple-choice test questions, 4 of them are based on photos of microscopic preparations discussed during the laboratories, the remaining ones concern the theoretical part discussed during laboratories, lectures and seminars in a given thematic section. The student must be familiar with the course book (recommended literature). For a correctly solved question, the Student receives 1 point. To pass the test, you must obtain a minimum of 21 points, i.e. correctly answer more than 50% of the questions. Final test score thresholds:

Very good (5.0) 37 - 40 points

Fairly good (4.5) 35 - 36 points

Good (4.0) 31 –34 points

Satisfactory plus (3.5) 28 - 30 points

Satisfactory (3.0) 21 - 27 points

• (2.0) 0 - 20 points

1. The first retake date for the final test takes the form of a written answer (essay) and is carried out within 7 days after the final test. The student answers 5 questions. For a correct and complete answer to the question, the Student receives 1 point. To pass the retake test, a minimum of 3 points should be obtained. Retake tests are assessed in the system: passed test (mark 3.0), failed test (mark 2.0). The second retake date for the final test takes place within 14 days before the final exam. If the second date of the retake test is not passed, the Student is not admitted to the final exam.

5. The final exam in the form of a test contains 130 multiple-choice questions. Thirty of them are based on photos of microscopic slides discussed during the laboratories, and the remaining ones concern the theoretical part discussed during laboratories, seminars and lectures. The student must be familiar with the course book (recommended literature).

In order to pass the final exam, you must obtain a minimum of 66 points. ie correctly answer more than 50% of the questions.

Final examination point thresholds:

Very good (5.0) 118– 130 points

Fairly good (4.5) 105 - 117 points

Good (4.0) 92 - 104 points

Satisfactory Plus (3.5) 79 - 91 points

Satisfactory (3.0) 66 - 78 points

Unsatisfactory (2.0) 0 - 65 points

The resit exam is identical to the final examination or consists of open-ended essay questions. The final grade for the Pathology subject is the grade from the final exam. 6. The remaining conditions are specified in the Study Regulations of the University of Zielona Góra https://www.uz.zgora.pl/index.php?regulamin-studiow

7. In matters not included in the regulations, the subject coordinator decides in consultation with the Head of the Department.

 

Literatura podstawowa

1. "Patologia znaczy słowo o chorobie". J. Stachura i W. Domagała. Wyd. PAU, Kraków, wyd. III, tom I, 2016 (ISBN 978-83-7676-241-8) i tom II, 2019 ISBN: 978-83-7676- 307-1)

2.„Podstawy patologii”. W. Domagała, M. Chosia, E. Urasińska. Wydawnictwo Lekarskie PZWL, 2010 (ISBN: 978-83-200-3499-8)

3.Atlas histopatologii”. W. Domagała, M. Chosia, E. Urasińska, Wydawnictwo Lekarskie PZWL, 2007 (ISBN 10:83-200-3476-0 lub ISBN 13:978-83-200-3476-9)

Further reading

Patologia Robbins  V. Kumar, A.K. Abbas, J.C. Aster  Edra Urban & Partner 2019   ISBN 978-83-66310-18-6

Literatura uzupełniająca

Uwagi

Zmodyfikowane przez dr Justyna Mazurek-Popczyk (ostatnia modyfikacja: 25-05-2023 21:21)